ANALYSIS OF BLOOD PARAMETERS AND COPROGRAM IN INFECTIOUS PATHOLOGIES OF THE ALIMENTARY TRACT IN DOGS
DOI:
https://doi.org/10.37406/2706-9052-2022-19Keywords:
dogs, infectious pathologies of alimentary tract, blood parameters, leukogram, coprogram.Abstract
Introduction. The body’s reaction to any disease is assessed not only by clinical signs, but also by the results of studies of the body’s biological substrates, which often allow revealing the degree and nature of pathological changes that occur in all systems and organs, which is important when choosing the most effective treatment regimen, as well as to identify subclinical disorders and contraindications to the use of certain drugs. Purpose. The purpose of work – to investigate the main blood parameters and coprogram in infectious pathologies of the alimentary tract in dogs. Methods. Experimental research was conducted during 2019–2021. Two groups of animals have been formed for research: control (healthy animals) and experimental (dogs with infectious enteritis). Haemato-biochemical and coprological studies have been performed using generally accepted methods. Results. In the process of studying the main blood parameters of dogs clinically suffering from infectious pathologies of the alimentary tract, moderate erythrocytopenia, persistent leukocytopenia, oligochromemia, hypoproteinemia, a decrease in blood colour index, haematocrit value, and an increase in ESR have been found. Leukogram parameters indicate the development of moderate neutrophilia, clearly expressed lymphocytopenia, which probably leads to the occurrence of immunosuppression and, accordingly, a more severe course of the disease. In the complex diagnosis of infectious gastroenteritis in dogs, studies of the excrement of sick animals are relevant, which make it possible to assess the functional state of the digestive system in these pathologies. The coprogram of dogs with an acute course of infectious enteropathies, compared to healthy animals on the same diet, has been characterized by an increased content of protein, stercobilinogen, bilirubin, undigested starch, soaps and neutral fat. Conclusion. Thus, changes in blood parameters and coprogram in infectious pathologies of the alimentary tract of dogs should be objectively taken into account when choosing therapeutic agents for their effective treatment.
References
Lisova V., Radsikhovskii N. Pathomorphological diagnostics of enteritis of viral etiology in dogs. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. 2018. Vol. 20. № 83. P. 299–303. DOI: 10.15421/nvlvet8360.
Clinical evaluation of hyperimmune plasma for treatment of dogs with naturally occurring parvoviral enteritis / R.A. Acciacca et al. Journal of Veterinary Emergency and Critical Care. 2020. Vol. 30. № 5. P. 525–533. DOI: 10.1111/vec.12987.
Canine circoviral hemorrhagic enteritis in a dog in Connecticut / H.J. Van Kruiningen et al. Journal of Veterinary Diagnostic Investigation. 2019. Vol. 31. № 5. P. 732–736. DOI: 10.1177/1040638719863102.
Prosyanуi S., Horiuk V. Epizootological features of manifestation of infectious enteritis of dogs in the conditions of Kamianets-Podilskyi district. Podilian Bulletin: Agriculture, Engineering, Economics. 2021. Vol. 1. № 33. P. 179–187. DOI: 10.37406/2706-9052-2020-2-20.
Assessing the Efficacy of Maropitant Versus Ondansetron in the Treatment of Dogs with Parvoviral Enteritis / L.A. Sullivan et al. Journal of the American Animal Hospital Association. 2018. Vol. 54. № 6. P. 338–343. DOI: 10.5326/jaaha-ms-6650.
Systolic dysfunction by two-dimensional speckle tracking echocardiography in dogs with parvoviral enteritis / C.B. de Abreu et al. Journal of Veterinary Cardiology. 2021. Vol. 34. P. 93–104. DOI: 10.1016/j.jvc.2021.01.006.
The role of the sequential organ failure assessment score in evaluating the outcome in dogs with parvoviral enteritis / L. Kalogianni et al. Research in Veterinary Science. 2022. Vol. 150. P. 44–51. DOI: 10.1016/j.rvsc.2022.05.014.
Parvovirus enteritis and other risk factors associated with persistent gastrointestinal signs in dogs later in life: a retrospective cohort study / K. Sato-Takada et al. BMC Veterinary Research. 2022. Vol. 18. № 1. P. 1–14. DOI: 10.1186/s12917-022-03187-7.
Prevalence of Salmonella in juvenile dogs affected with parvoviral enteritis / W.J. Botha et al. Journal of the South African Veterinary Association. 2018. Vol. 89. P. 1–6. DOI: 10.4102/jsava.v89i0.1731.
Canine Parvovirus Infection in Dogs: Prevalence and Associated Risk Factors in Egypt / M.Z. Sayed-Ahmed et al. World’s Veterinary Journal. 2020. Vol. 10. № 4. P. 571–577. DOI: 10.54203/scil.2020.wvj68.
Parvovirus enteritis and other risk factors associated with persistent gastrointestinal signs in dogs later in life: a retrospective cohort study / K. Sato-Takada et al. BMC Veterinary Research. 2022. Vol. 18. № 1. P. 1–14. DOI: 10.1186/s12917-022-03187-7
Altered blood procalcitonin, C-reactive protein, and leucocytes count in association with canine parvovirus (CPV) enteritis / A.A. Kubesy et al. Comparative Clinical Pathology. 2019. Vol. 28. № 4. P. 1095–1099. DOI: 10.1007/s00580-019-02941-y.
Clinical, haemato-biochemical alterations with acute phase response in canine parvoviral enteritis / I. Abdullaziz et al. Damanhour Journal of Veterinary Sciences. 2022. Vol. 7. № 1. P. 23–27. DOI: 10.21608/djvs.2022.103638.1057.
Goddard A., Leisewitz A. L. Canine Parvovirus. Veterinary Clinics of North America: Small Animal Practice. 2010. Vol. 40. № 6. P. 1041–1053. DOI: 10.1016/j.cvsm.2010.07.007.
Efficacy of feline anti-parvovirus antibodies in the treatment of canine parvovirus infection / M. Gerlach et al. Journal of Small Animal Practice. 2017. Vol. 58. № 7. P. 408–415. DOI: 10.1111/jsap.12676.
Long-term effects of canine parvovirus infection in dogs / E. Kilian et al. PLOS ONE. 2018. Vol. 13. № 3. P. e0192198. DOI: 10.1371/journal.pone.0192198.
